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Page 6 of 15  Original Research


                                                             A1                                                  B1
                                                                     25
                  110
                                                                     20
                  100                                                15                                  +1.96 SD
                                                                                                           15.6
                  90                                                 10
                Jaffe 4hr μmol/l  80                               (enzyma c 4hr- jaffe 4hr) / Mean %  5 0  Mean

                                                                                                           1.8
                  70
                                                                     -5
                  60                                                -10                                   -1.96 SD
                  50                                                -15                                   -12.0

                  40                                                -20
                    40    50   60    70   80    90   100  110          50   60    70    80    90   100   110  120
                                 Enzyma c 4hr μmol/l                         Mean of enzyma c 4hr and jaffe 4hr μmol/l
                                                             A2                                                  B2
                  110                                               40
                                                                    30
                  100                                                                                     +1.96 SD

                  90                                                20                                     20.7
                                                                    10
                Jaffe 6hr μmol/l  80                               (enzyma c6hr - jaffe 6hr) / Mean %  -10 0  Mean


                                                                                                           -4.7
                  70
                  60                                                -20                                   -1.96 SD
                                                                    -30
                  50                                                                                       -30.2
                                                                    -40
                  40                                                -50
                    40    50    60    70   80    90   100   110        40    50    60    70    80    90   100   110
                                  Enzyma c 6hr μmol/l                         Mean of enzyma c 6hr and jaffe 6hr μmol/l
                                                             A3                                                  B3
                  140                                                40
                  130                                                                                      -1.96 SD
                  120                                                20                                     14.9
                  110                                                0
                Jaffe 24hr μmol/l  100                              (enzyma c 24hr - jaffe 24hr) / Mean %  -20  Mean

                  90
                                                                                                            -17.8
                  80
                  70                                                -40                                    -1.96 SD
                  60                                                -60                                     -50.5
                  50
                  40                                                -80
                    40      60      80      100     120     140        40        60         80        100        120
                                  Enzyma c 24hr μmol/l                       Mean of enzyma c 24hr and jaffe 24hr μmol/l
              FIGURE 3: Passing-Bablok regression curves (A) and Bland-Altman plots (B) comparing creatinine concentrations from the kinetic Jaffe method with those from the
              enzymatic method. Creatinine concentrations at (1) < 4 h, (2) 6 h, (3) 24 h, (4) 48 h, (5) 72 h and (6) 96 h.
                                                                                                 Figure 3 continues on the next page →


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