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Southern African Journal of HIV Medicine
              ISSN: (Online) 2078-6751, (Print) 1608-9693
                                                       Page 1 of 7  Original Research


                               Evaluation of a mobile application to

                           support HIV self-testing in Johannesburg,

                                                      South Africa






               Authors:                 Background: Human immunodeficiency virus self-testing (HIVST) reduces barriers associated
               Natasha Gous   1         with facility-based testing; however, no formal mechanism exists for users to self-report results
               Alex E. Fischer   2                             TM
               Naleni Rhagnath          or link to care. The Aspect  HIVST mobile application (app) was developed for use in
                         2
               Mothepane Phatsoane   2  South Africa.
               Mohammed Majam
                           2
                                                                                                       TM
               Samanta T. Lalla-Edward   2  Objectives: This study evaluated the acceptability and feasibility of the Aspect  HIVST app
                                        for individuals from the inner city of Johannesburg.
               Affiliations:
               1 SystemOne, LLC,        Method: This cross-sectional pilot, with a convenience sample of 300 adults, was conducted in
               Weltevreden Park,        July 2018. Participants were provided an OraQuick HIVST kit and a smartphone preloaded
               South Africa             with the app, then asked to follow the in-app instructions for use (IFU) to complete the HIVST
                                        and upload results. Trained healthcare workers (HCWs) observed and recorded any deviations
               2 Ezintsha, Wits Reproductive
               Health and HIV Institute,   from the IFU, and conducted a post-test survey to assess acceptability. Feasibility was evaluated
               University of the        by the number of participants who agreed to participate, completed the self-test, and uploaded
               Witwatersrand,           all information onto the app correctly.
               Johannesburg, South Africa
                                        Results: Most participants (98.7%) found the app easy to use. To reduce difficulties related to
               Corresponding author:    the IFU (26; 8.7%), participants suggested multimedia supplements (4; 1.3%), additional
               Alex Fischer,            languages (4; 1.3%) and simplified instructions (5; 1.7%). All individuals approached, agreed
               [email protected]
                                        to participate, 267 (89.0%) correctly completed all steps and 210 (78.7%) successfully captured
               Dates:                   all information on the app. Most errors (26; 8.7%) were testing errors and 1 (0.3%) was from the
               Received: 25 Mar. 2020   app sequence. Twelve (4.5%) errors were with test strip imaging and 72 (27.0%) discordances
               Accepted: 23 Apr. 2020
               Published: 30 June 2020  were with demographic information.
                                        Conclusion: Despite some challenges with IFU interpretation and data capture via the app,
               How to cite this article:
                                                                   TM
               Gous N, Fischer AE,      this pilot showed that the Aspect  HIVST app is an acceptable way to upload mobile HIVST
               Rhagnath N, Phatsoane M,   results and demographic information to a central database.
               Majam M, Lalla-Edward ST.
               Evaluation of a mobile   Keywords: HIV self-test; digitisation; mobile app; monitoring and evaluation; digital health.
               application to support HIV
               self-testing in Johannesburg,
               South Africa. S Afr J HIV Med.   Introduction
               2020;21(1):a1088. https://
               doi.org/10.4102/sajhivmed.  In 2012, the OraQuick  ADVANCE Rapid HIV-1/2  Antibody Test (OraSure Technologies Inc,
               v21i1.1088
                                       Bethlehem, USA) was the first HIV self-test (HIVST) approved for sale in the United States as an
               Copyright:              over-the-counter HIVST rapid diagnostic test (RDT) for individuals with no prior HIV testing
               © 2020. The Authors.    experience.  Since then, over 2.5 million HIVST kits have been sold globally and more than 4
                                                1
               Licensee: AOSIS. This work   million have been distributed through donor funded programmes.  The World Health Organization
                                                                                          2
               is licensed under the   (WHO) strongly recommends that HIVST be utilised as a way to complement existing HIV
               Creative Commons
                                             3
               Attribution License.    services  as self-testing may reduce barriers associated with traditional facility-based testing, like
                                       travel, wait times and privacy concerns. 4,5
                                       Based on this growing body of evidence, South Africa became one of over 40 countries to have
                                                                                        6,7
                                       incorporated HIV self-testing into their national HIV policies,  with self-testing introduced as a
                                       way to help close the gap between the 84.9% of adults living with HIV who know their HIV status
                                       and the 90% target of the UNAIDS 90-90-90 initiative. 5,8,9,10  The introduction of HIVST programmes
                                       will improve access to further HIV diagnostic services, prompting an increase in testing uptake
               Read online:            and frequency, which could lead to earlier diagnosis. 11
               Read online:
                        Scan this QR
                        Scan this QR
                        code with your
                        code with your   There are, however, several concerns related to HIVST, as there is no formal pipeline for users to
                        smart phone or
                        smart phone or
                        mobile device   self-report their results or be linked to care following the self-test. These HIVST kits are not
                        mobile device
                        to read online.
                        to read online.
                                       diagnostic, but rather considered tests for triage, and all positive results should prompt the user
                                           http://www.sajhivmed.org.za 180  Open Access
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