Page 343 - SAHCS HIVMed Journal Vol 20 No 1 2019

Page 5 of 5 Original Research

a record-keeping system was initiated where the clinical staff of Authors’ contributions
the paediatric clinic record the mother’s contact details; however, C.B., J.C., Z.I., L.v.d.L. and L.W. were the medical students
the infant’s treatment should also be recorded.
who compiled the protocol, performed the data collection
and wrote the first draft report of this study. R.v.Z. was the
Recommendations study leader from the project’s inception. G.J. advised with
The maternity ward and paediatric clinic at MUCPP CHC the planning of the study, performed the analysis and assisted
should establish a more detailed record-keeping system and with the write-up.
improve the communication between the two departments to
keep track of testing, results and patient follow-up to provide References
a continuum of care through the postnatal period. A written
date for the 10-week follow-up test should be given on an 1. UNAIDS. Children [homepage on the Internet]. 2017 [cited 2018 Feb 28]. Available
from: http://www.unaids.org/en/topic/children.
appointment card to the mother or caregiver. The maternity 2. Anoje C, Aiyenigba B, Suzuki C, et al. Reducing mother-to-child transmission of
ward and paediatric clinic should also record that the date HIV: Findings from an early infant diagnosis program in south-south region of
Nigeria. BMC Public Health. 2012;12:184. https://doi.org/10.1186/1471-
was given to the mother or caregiver. 2458-12-184
3. Chiu A, Modi S, Rivadeneira ED, Koumans EH. Optimizing infant HIV diagnosis in
resource-limited settings: Modeling the impact of HIV DNA PCR testing at birth. J
A future study could be conducted to determine whether Acquir Immune Defic Syndr. 2016;73(4):454–462. https://doi.org/10.1097/
infants who tested positive at birth had a confirmatory test. QAI.0000000000001126
In addition, infant follow-up testing through 18 months of 4. Taylor D, Durigon M, Davis H, et al. Probability of a false-negative HIV antibody
test result during the window period: A tool for pre- and post-test counselling. Int
age should be documented. Feedback should be given to the J STD AIDS. 2015;26(4):215–224. https://doi.org/10.1177/0956462414542987
clinic and HIV programme. This setting is ideal for a 5. Laughton B, Cornell M, Grove D, et al. Early antiretroviral therapy improves
neurodevelopmental outcomes in infants. AIDS. 2012;26(13):1685–1690. https://
continuous quality improvement programme. 13 doi.org/10.1097/QAD.0b013e328355d0ce
6. Violari A, Cotton MF, Gibb DM, et al. Early antiretroviral therapy and mortality
Acknowledgements among HIV-infected infants. N Engl J Med. 2008;359(21):2233–2244. https://doi.
org/10.1056/NEJMoa0800971
7. National Department of Health. The National consolidated guidelines for the
The authors thank Mrs P. Meningwa and Mrs O. Mocumi prevention of mother-to-child transmission of HIV (PMTCT) and management of
at the Mangaung University Community Partnership HIV in children, adolescents and adults. Pretoria: Department of Health, Republic
of South Africa; 2015.
Programme Community Health Centre for allowing them 8. AIDS Info. Guidelines for the use of antiretroviral agents in paediatric HIV
access to the mothers’ files and birth register, and Prof. infection [homepage on the Internet]. 2016 [update 2018 Dec 14; cited 2016
Dec 17]. Available from: https://aidsinfo.nih.gov/guidelines/html/2/pediatric-
J. Goedhals and Dr S. Vawda, Department of Virology, arv/0.
University of the Free State (UFS), for allowing them access 9. Haeri Mazanderani AF, Du Plessis NM, Thomas WN, Venter E, Avenant T. Loss of
detectability and indeterminate results: Challenges facing HIV infant diagnosis in
to the NHLS to collect data. They are also grateful to Mrs A. South Africa’s expanding ART programme. S Afr Med J. 2014;104(8):574–577.
Bouwer, research coordinator, Department of Paediatrics and https://doi.org/10.7196/samj.8322
Child Health, UFS, for her assistance with the report, and 10. Dekker B. Evidence on: Advanced maternal age [homepage on the Internet].
Evidence Based Birth®. 2016 [cited 2018 Feb 26]. Available from: https://
Ms T. Mulder, medical editor and writer, Faculty of Health evidencebasedbirth.com/advanced-maternal-age/.
Sciences, UFS, for preparation of the manuscript. 11. UNAIDS. Data 2017 [homepage on the Internet]. 2017 [cited 2018 Feb 28].
Available from: http://www.unaids.org/sites/default/files/media_asset/20170
720_Data_book_2017_en.pdf.
Competing interests 12. National Department of Health. Clinical Guidelines: PMTCT (prevention of
mother-to-child transmission) 2010. Pretoria: Department of Health, Republic of
South Africa; 2010.
The authors declare that they have no financial or personal 13. Youngleson MS, Nkurunziza P, Jennings K, Arendse J, Mate KS, Barker P. Improving
relationships that may have inappropriately influenced them a mother to child HIV transmission programme through health system redesign:
Quality improvement, protocol adjustment and resource addition. PLoS One.
in writing this article. 2010;5(11):e13891. https://doi.org/10.1371/journal.pone.0013891

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