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Page 7 of 8  Original Research


              Unemployment,  gender, age  and  distance  to  a healthcare   Having two or more NCDs was markedly associated with
              facility are well-known key determinants of health.  In this   more days spent without undertaking usual daily activities
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              study, significant associations were found between these key   and more money spent on medication, compared with cases
              determinants of health and the ability to purchase prescribed   with one NCD. Having more than one NCD naturally
              medication, as well as days spent without carrying out usual   translates to more money needed to purchase medication,
              daily activities because of illness. This finding can be   thus increasing  the possibility  of inability  to purchase the
              explained in part by the fact that the majority of employed   required medication, especially given the fact that the
              participants in the study were men, below the age of 60 years.   majority of the participants were either unemployed or had
              Given that antihypertensives and diabetic medications were   an unstable source of income. Without access to prescribed
              largely  accessible  through  out-of-pocket  payment,  medication  to  manage their  health,  patients  would be
              employment enables those with NCDs to purchase the    predisposed to poorer health outcomes as indicated by
              prescribed medications and take control of their health. In   productive days lost because of illness observed in this study.
              patriarchal  societies,  such  as  Zimbabwe,  opportunities  for   Patients were more likely to opt for alternative medication
              income and control of resources are biased towards the male   from informal sources to manage their health in the face of
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              gender compared with females.  The female gender and   limited or no income to purchase prescribed medication.
              unemployment are inextricably linked together in such
              societies, predisposing unemployed female participants to   Use of alternative medication was commonly reported
              negative health outcome, as observed in this study.   among cases as compared with controls. However, use of
                                                                    alternative medication was not associated with positive
              On the other hand, the lower proportion of male participants   improvements on days spent without undertaking daily
              and the fewer number of days these male participants spent   activities because of sickness. Use of alternative medication
              without undertaking usual daily activities because of illness,   may have been influenced to some extent by the cases’
              compared  with  female  participants,  needs  further  inquiry.   inability to purchase NCD medication, forcing patients to
              Observed findings could have been influenced in part by   resort to cheaper alternatives to manage ill health. This could
              poor health seeking behaviours, which are commonly    be assumed, given that the controls did not report use of
              associated with the male gender.  Because of their    alternative medication for management of HIV other than
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              masculinity, characteristic of men, participants might   ART. Common alternative medication included home
              deliberately under-report the number of days they spent   remedies and traditional herbs that are readily available at
              without carrying out usual daily activities. Perhaps, the   lower  costs.  Toxicity,  maximum safe  dosage  and  clinical
              perception of serious ill health  in men might be different   efficacy for these treatment options are usually not known,
              from that in women. 12,13,14                          thus potentially predisposing the users to other unknown
                                                                    negative health consequences.  Future studies should assess
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              In general, cases were found to spend more days without   the various types and sources of alternative medications
              undertaking usual daily activities because of illness compared   commonly used by this patient population to gain a better
              with controls. A study conducted in Namibia found similar   understanding about this issue.
              results, where sickness because of HTN and DM was the top
              cause of absenteeism among workers in the formal sector.    Higher out-of-pocket medication and transport expenses
                                                             15
              Cases aged 60–69 years and ≥ 70 years were more likely to   faced by cases can push patients to employ various coping
              spend more days without carrying out usual daily activities   mechanisms,  including  cutting  back  on  medication  use  to
              or tasks because of illness. They were more at risk of not being   adopt traditional medication  or forgoing other basic
              able to purchase NCD medication, compared with other age   necessities including food.  Finally, we need further enquiry
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              categories, and compared with similar age categories in   to better understand challenges experienced by people with
              controls, after controlling for potential confounders.   HIV-NCD comorbidity (especially the difficulties faced in
                                                                    accessing medication and care) and the coping mechanisms
              Productivity  days  lost  because  of  illness  are  linked  with   that they employ in dealing with these challenges.
              lower income or loss of employment or limited opportunities
              for work, which translates to lack of income to purchase the   Study limitations
              needed medication. A study conducted in USA  found out-
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              of-pocket medication costs to be a significant challenge faced   •  Measurement of the outcome variable, ‘number of days
              by older adults with DM, often forcing them to cut back on   spent by participants without doing usual daily activities
              medication use, forgoing food or other basic necessities or   or tasks’, was based on self-reported responses by
              borrowing money. The age group  ≥60 years is usually    participants and not objectively ascertained.  Although
              associated with retirement and diminished ability and   effort was put in corroborating individual responses with
              opportunities for employment.  When medication for NCDs   further follow-up questions, there is a possibility that
                                      17
              has to be purchased through out-of-pocket payments, this   variations in personal characteristics could have affected
              age group is at risk because of inability to afford medication   how participants responded to ill health (to do or not to
              and consequently face a greater risk for the observed poorer   do usual daily tasks). Again, recall bias cannot be ruled
              health outcomes.                                        out in the measurement of this variable. However, we

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