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Page 4 of 9  Original Research


              TABLE 2: Socio-demographic and categorical variables of the study participants.
              Socio-demographics                Study participants (n = 17)               Control group (n = 17)
                                      Median     IQR        n        %         Median     IQR        n        %
              Age in years              38       35–42      -         -          38      35–42       -         -
              BMI                       25       21–25      -         -          25      21–25       -         -
              Duration of ART treatment years   5  3–5      -         -          0         0         -         -
              Duration of haemodialysis in years  3  3–4    -         -          6        3–6        -         -
              Sex
              Male                      -         -         9        53          -         -         9        53
              Female                    -         -         8        47          -         -         8        47
              Comorbidities
              Hypertension              -         -        17        100         -         -        16        94
              Diabetes mellitus         -         -         0         0          -         -         1         6
              Social history
              Reported smoking          -         -         0         0          -         -         0         0
              Reported alcohol use      -         -         0         0          -         -         0         0
              Reported recreational drug use  -   -         0         0          -         -         0         0
              Chronic infections
              Mycobacterium tuberculosis  -       -         0         0          -         -         0         0
              Hepatitis B               -         -         1        0.1         -         -         0         0
              Cause for renal failure
              Hypertension              -         -        14        82          -         -        16        94
              Diabetes mellitus         -         -         0         0          -         -         1         6
              HIVAN                     -         -         2        12          -         -         0         0
              Other                     -         -         1        0.1         -         -         0         0
              BMI, body mass index; ART, antiretroviral therapy; HIVAN, HIV-associated nephropathy; IQR, interquartile range.
              TABLE 3: Measured parameters of the study controls.
              Variables  WCC (× 10^9/L)  % of CD3+ cells   Absolute CD3    % of CD4+Tcells   Absolute CD4    % of CD8+ T cells  Absolute CD8 cells
                                    lymphocytes   count (cells/µL)           count (cells/µL)              (cells/µL)
                      Pre-  Post-   Pre-  Post-   Pre-  Post-   Pre-  Post-   Pre-  Post-   Pre-  Post-  Pre-  Post-
                     dialysis  dialysis  dialysis  dialysis  dialysis  dialysis  dialysis  dialysis  dialysis  dialysis  dialysis  dialysis  dialysis  dialysis
              1       4.07  4.33    79.8  80.7    990   1011    29.4  30.5    291   309    38.8   39.3    384   397
              2       3.71  4.57    81.1  82.1    1184  1395    43.5  50      515   698    20.2   18.4    239   257
              3       3.51  3.46    72.5  74.3    403   1023    39.6  44.6    404   456    15.4   16.3    157   167
              4       3.21  3.68    83.5  83.7    702   619     45.9  47.8    322   296    23.4   20.9    170   129
              5       8.20  5.56    69.4  74.7    1983  1930    43.4  48.8    861   942    24.4   23.0    483   444
              6       1.51  1.87    67.5  74.0    678   592     35.7  37.1    242   220    31.5   28.1    214   167
              7       4.76  4.12    75.6  75.6    1280  1125    44.7  47.7    573   537    35.7   34.9    457   393
              *8      5.06  3.80     -     -       -     -      36.2  41.6    424   476     -      -      -     -
              *9      3.18  3.23     -     -       -     -      44.6  44.7    432   442     -      -      -     -
              *10     5.55  5.41     -     -       -     -      46.4  54.7    465   498     -      -      -     -
              *11     3.74  4.33     -     -       -     -      46.7  53.3    236   363     -      -      -     -
              12      3.93  4.87    75.6  79.9    977   806     34.5  52.9    337   427    30.1   23.2    294   187
              13      4.70  4.63    78.8  80.3    606   564     35.9  47.1    218   265    23.6   21.1    143   119
              14      5.32  5.18    71.5  81.1    1290  743     51.1  53.2    659   395    23.2   22.0    299   163
              15      3.61  3.75    74.1  73.8    844   904     45.2  45.5    382   412    15.9   19.7    134   178
              16      5.01  4.16    71.9  77.3    587   1652    31.3  52.5    268   868    21.8   22.0    272   364
              17      2.78  2.02    76.5  73.2    779   490     44.8  50.4    349   247    23.9   21.6    186   106
              Mean    4.24  4.05    76.9  75.7    946   998     41.1  47.2    410   461    25.2   23.9    264   236
              SD      1.50  1.03    5.7   5.7     416   441     6.2   6.3     168   204    7.01   6.5     116   120
              WCC, white cell count.

              All the study participants’ total leukocyte counts, absolute   CD4+ T-cell count of < 200 cells/µL (Table 4). See Table 5 for
              CD3+  T-cell  counts  and  the  absolute  CD8+  T-cell  counts   reference ranges.
              were within the normal laboratory reference range for
              adults. The pre-dialysis absolute CD4+ T-cell count was   For the study participants, no statistically significant change
              lower than the normal laboratory reference range in eight   was observed in the total leukocyte count (t = 0.5178,
              HIV-infected patients (47%), and two patients had an   p  =  0.612), the T-cells (CD3+ cells) as a percentage of the
              absolute  CD4+ T-cell count  of  < 200 cells/µL. The  post-  lymphocyte count. (t = 1.609,  p = 0.142) or the absolute
              dialysis absolute CD4+ T-cell counts were lower than the   CD3+ T-cell count (t = 0.122, p = 0.901) after haemodialysis.
              normal reference range in six (35%) of the HIV-infected   A statistically significant increase was noted in the post-
              patients. Only one patient presented with an absolute   dialysis CD4+ T cells as a percentage of lymphocytes (t =

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