Page 211 - SAHCS HIVMed Journal Vol 20 No 1 2019
P. 211

Page 5 of 6  Original Research


              There was no difference in in-hospital mortality between   Thus, in addition to AIDS-defining illnesses, clinicians must
              HIV-positive and HIV-negative surgical inpatients. This   have a high index of suspicion for squamous cell carcinoma
              contrasts with a study in Malawi, which, in a small cohort,   and  oesophageal,  anal,  penile  cancers  in  HIV-positive
              found a higher mortality rate in HIV-positive patients. 17  patients. In countries experiencing a high prevalence of HIV,
                                                                    surgical training programmes and surgical units in hospitals
              In several studies from SSA, most of them in the pre-ART era,   must anticipate the types of surgeries that HIV-positive
              a significant difference in surgical outcomes and complications   patients are likely to require, such as excision of malignancies,
                          20
              was not found.  However, there seems to be evidence for a   and provide adequate training, staffing and facilities to meet
              higher mortality rate in HIV-positive patients undergoing   the needs for the future.
              emergency surgery. 21
                                                                    Acknowledgements
              HIV and malignancies                                  Competing interests

              In addition to the known AIDS-defining malignancies, HIV-  The authors declare that there were no conflicts of interest
              infected patients are also more likely to suffer from certain   during the writing of this article.
                    5
              cancers.  In our study, there was a strong correlation between
              HIV and certain malignancies. In the adult age group 15–49
              years, 46.3% of the patients with proven malignancies were   Authors’ contributions
              HIV-positive. Unsurprisingly, HIV prevalence was highest   P.M. performed data collection, data analysis and
              among cervical cancer patients (63.2%). In addition to this,   interpretation, wrote the article and acted as the corresponding
              however, we  found a higher  prevalence  (51.4%) in the   author. M.S. supervised  development  of the  article  and
              squamous cell carcinoma group and a 2.54-fold greater   helped in data interpretation and manuscript evaluation. P.T.
              likelihood of having HIV. Oesophageal, skin and penile   conceived of the presented idea and helped in manuscript
              cancers were also common in HIV-positive patients. The   evaluation. P.M. and P.T. designed the study and developed
              association with HPV and penile cancer is well established.    the methodology.
                                                             22
              While ART has decreased the incidence of NHL, more cases
              of oesophageal cancer and stomach cancer are being    References
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