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Strength/weakness of design The strengths of this study include the large and representative cohort; the 31 033 HIV-infected ART-naive adults included in this analysis represent 24% of all adult patients enrolled in care in Rwanda between 2005 and 2010. Patients in the analysis came from 41 different health facilities ranging in size from primary health clinics to large district hospitals and were located in both rural and urban areas. The use of routinely collected

Major outcomes of study There were higher rates of ART initiation within 3 months amongst patients who were ART eligible at enrollment. From 2006 to 2011, earlier initiation of ART after eligibility was observed likely reflecting improved programme quality. The Rwanda National HIV Care and Treatment Programme have achieved significant success in scaling up ART with 94% of eligible patients receiving treatment in 2012. Rwanda was also one of the first countries in

Study location Rwanda Addis Ababa (Ethiopia) Swaziland

The study examined time to ART eligibility amongst adult patients (≥ 15 years of age) and time to ART initiation amongst eligible patients receiving care at health facilities in Rwanda Study estimated the total number of patients who would need ART if Ethiopia guidelines, the number of patients needing ART based on current guidelines were added to the number of asymptomatic patients enrolled in pre-ART with a CD4+ count > 200 but The study measure

Study focus from 2005 to 2010 according to WHO guidelines. adopted the 2010 ≤ 350 cells/mm 3 . implementing UTT, retention and viral patient per year.

Type of study Retrospective study Retrospective and prospective medical chart reviews Prospective 3-year stepped- wedge randomised control study

Study objectives Determine time to ART initiation amongst patients eligible at enrollment compared with those ineligible or of indeterminate eligibility who become eligible during follow-up The study assessed the implications of implementing the WHO’s 2010 guidelines for ART initiation in adults and adolescents with HIV-infection compared with the earlier threshold. The study was designed to determine the feasibility, acceptability, affordability

TABLE 1 (Continues...): Summary of studies. Theme identified Guidelines year Timely implementation of 2006 and WHO and ART initiation 2010 policy guidelines at country level Adoption of WHO and ART initiation policy guidelines at national level Barriers and facilitators to WHO policy implementation Timely implementation of 2010 WHO and ART initiation policy guidelines at country level Adoption of WHO and ART initiation policy guidelines at country leve

Teasdale
and year
Paper 14
Paper 15
Konings
Author
et al. 23
et al. 22
2012
2015
http://www.sajhivmed.org.za 226 Open Access Walsh et al. 24 2017 Paper 16