Page 150 - SAHCS HIVMed Journal Vol 20 No 1 2019
P. 150

Page 3 of 8  Original Research


              Ethical consideration                                 TABLE  1:  Summary  of  socio-demographic  characteristics  of  adolescents  and
                                                                    young adults (aged 16–24 years) by gender.
                                                                                                       Females
                                                                                              Males
              The study protocol, informed consent and other materials   Characteristic (n)†  (n = 1417)  (n = 1963)  p
              were approved by the Botswana Health Research                                  n   %    n    %
              Development Committee, and the US Centers for Disease   Education level (n = 3373)                0.02
              Control and Prevention, the two governing Institutional   None or primary      89   6   92   5
              Review Boards for the BCPP study. Written informed    Secondary               1147  81  1562  80
              consent was obtained from all participants aged 18 years   Tertiary           180  13   303  15
              and above, while participants aged 16–17 years provided   Sexually active (n = 3380)  815  58  1496  76  < 0.0001
              written assent, with parents or guardians providing   HIV status (n = 3372)                     < 0.0001
              written permission.                                   Positive                 37   3   183  9
                                                                    Negative                1377  97  1775  91
              Results                                               Household food insecurity (n = 3334)  960  69  1358  70  0.62
                                                                    Never
                                                                    Rarely                  198  14   247  13
              Among the 12 610 individuals who consented or assented   Sometimes            182  13   250  13
              with parental permission to participate in the parent study   Often            55   4   84   4
              at the initial baseline visit, 3413 were adolescents and   Refrigeration in household (n = 3165)  641  51  863  47  0.28
              young adults aged 16–24 years. A total of 3380 responded   Cooking source in household (n = 3336)  0.10
              to the sexual activity questionnaire, with 2311 (68%)   Gas                   356  26   444  23
              reporting  prior engagement  in  sexual activity  and  1069   Electricity     235  17   336  17
              (31%) reporting never having been sexually active. The   Charcoal/wood        799  57  1144  59
              majority (~80%) of participants reported a secondary level   Other             5   < 1  17   1    0.11
                                                                    Water source (n = 3335)
              education.  A higher proportion of sexually active    Piped indoors           169  12   255  13
              individuals reported lack of television (44% vs. 37%; p <   Standpipe or tap in yard  888  64  1155  60
              0.0001) or refrigeration (55% vs. 46%;  p < 0.0001) and   Communal stand pipe  306  22  483  25
              reliance on a communal stand pipe for water (26% vs. 20%;   Other              32   2   47   2
              p < 0.0001).                                          Toilet type (n = 3336)                      0.09
                                                                    Flush toilet in home    230  17   340  18
                                                                    Pit latrine in yard     1021  73  1366  70
              Female participants were significantly more likely to report
              ever being sexually active than males (76% vs 58%,    Communal toilet/pit latrine  100  7 3  143  7 5
                                                                                                      92
                                                                    Bush or other
                                                                                             44
              respectively; p < 0.0001) (Table 1). Among all adolescents and   Television in home (n = 3165)  788  40  1044  57  0.07
              young adults, regardless of history of being sexually active,   Access to internet (n = 3165)  169  13  237  13  0.99
              93% were HIV-uninfected at the time of the survey. Among   Own a cell phone (n = 3165)  1252  95  1747  95  0.51
              the 1069 individuals reporting no prior sexual activity,   Community population size in quartiles (n = 3380)  0.68
              36  (3%) were HIV-infected, of whom 30 (83%) were     2700 to 3899 persons    223  16   332  17
              adolescents, whereas 184 (8%) individuals reporting prior   3900 to 5199 persons  360  25  502  26
              sexual activity were HIV-infected, with 85% of the infections   5200 to 7499 persons  378  27  493  25
                                                                                            456
                                                                                                           32
                                                                    7500 to 12 850 persons
                                                                                                      636
                                                                                                 32
              occurring in young adults aged 20–24 years. Twelve (33%) of   Distance from an urban area, in quartiles (n = 3380)  0.99
              the individuals with HIV who reported no prior sexual   18 to 24 km           268  19   377  19
              activity had documentation of diagnosis prior to 10 years of   24 to 40 km    467  33   640  33
              age, suggesting perinatal acquisition of HIV, while nine (25%)   41 to 84 km  246  17   340  17
              were newly diagnosed with HIV during the YaTsie baseline   85 to 380 km       436  31   606  31
              household HIV testing.                                †,  ‘n’  of  <  3380  for  any  socio-demographic  variable  reflects  lack  of  response  from  the
                                                                    participant to that question.
              Risky sexual practices by gender                      Predictors of gender-specific engagement in
              Among the sexually active respondents, we evaluated risky   high-risk sexual practices
              sexual practices by gender (Table 2). Compared with males,   We modelled factors associated with risky sexual practices,
              females were significantly more likely to report inconsistent   stratified by gender. For females, factors associated with
              condom use (PR 1.61; 95% CI 1.44–1.80), intergenerational   consistent condom use, intergenerational sex with a
              sex (PR 9.00; 95% CI 5.84–13.88) and transactional sex   partner  ≥ 10 years older and transactional sex were
              (PR3.46;  95%  CI  2.07–5.77)  during  the  prior  12  months.   modelled. For males, factors associated with early sexual
              However, female participants were significantly less likely   debut, alcohol use with sex and ≥ two sex partners in the
              to report having engaged in sex before 15 years of age (PR   last 12 months were modelled (Table 3).  Young adult
              0.59; 95% CI 0.41–0.85), report use of alcohol (by either   females aged 20–24 years were 30% (PR 1.30; 95% CI 1.13–
              partner) during sexual intercourse (PR 0.59; 95% CI 0.45–  1.49) more likely to report inconsistent condom use
              0.76) or having ≥ two partners in the last 12 months (PR 0.65;   compared with adolescent females aged 16–19 years. In
              95% CI 0.57–0.74).                                    multivariate analysis, a positive HIV status was associated

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