Page 27 - HIVMED_v21_i1.indb

Southern African Journal of HIV Medicine
ISSN: (Online) 2078-6751, (Print) 1608-9693
Page 1 of 39 Guideline

Southern African HIV Clinicians Society guidelines for

antiretroviral therapy in adults: 2020 update

Authors: Table of contents
Jeremy Nel 1
Sipho Dlamini 2
Graeme Meintjes 3 What is new in the 2020 guidelines update? ..............................................................................1
Rosie Burton 4
5
John M. Black 1. Preamble .............................................................................................................................1
Natasha E.C.G. Davies 6
Eric Hefer 2. Nucleoside or nucleotide reverse transcriptase inhibitor class of
7
Gary Maartens 8 antiretroviral drugs .............................................................................................................3
Phetho M. Mangena 9,10
11
Moeketsi T. Mathe 3. Integrase strand transfer inhibitor class of antiretroviral drugs ..........................................5
12
Mahomed-Yunus Moosa
Muhangwi B. Mulaudzi 4. Non-nucleoside reverse transcriptase inhibitor class of antiretroviral drugs .....................6
13
Michelle Moorhouse
14
Jennifer Nash 5. Protease inhibitor class of antiretroviral drugs ...................................................................8
15
Thandeka C. Nkonyane 16, 17
Wolfgang Preiser 18,19 6. Initiation and timing of antiretroviral therapy ....................................................................9
Mohammed S. Rassool
20
David Stead 21, 22 7. Baseline investigations ......................................................................................................11
Helen van der Plas 2
Cloete van Vuuren 23, 24 8. Viral load ...........................................................................................................................11
Willem D.F. Venter
25
+
Joana F. Woods 9. CD4 count ........................................................................................................................13
25
Affiliations: 10. Resistance and genotyping ...............................................................................................14
1 Helen Joseph
Hospital, Department 11. Initial antiretroviral therapy regimens for the previously untreated patient ....................16
of Medicine, University
of the Witwatersrand, 12. Management of patients currently receiving first-line therapy ........................................17
Johannesburg, South Africa
13. Management of patients starting or currently receiving second-line therapy .................19
2 Department of Infectious
Diseases, Faculty of Medicine, 14. Third-line antiretroviral therapy .......................................................................................21
University of Cape Town, 15. Laboratory monitoring of the efficacy and safety of antiretroviral therapy .....................22
Cape Town, South Africa
16. Patients who return after stopping antiretroviral therapy ................................................23
3 Department of Medicine,
Division of Infectious 17. Drug–drug interactions .....................................................................................................24
Diseases and HIV Medicine,
Groote Schuur Hospital, 18. Tuberculosis ......................................................................................................................25
University of Cape Town,
Cape Town, South Africa 19. Pregnancy and breastfeeding ...........................................................................................26
4 Southern African Medical 20. Liver disease......................................................................................................................28
Unit, Médecins Sans Frontières
(MSF), Cape Town, South 21. Renal disease ....................................................................................................................29
Africa
22. Psychiatric disease ............................................................................................................30
5 Department of Medicine, 23. Malaria ..............................................................................................................................30
Division of Infectious
Diseases, Livingstone Tertiary 24. Antiretroviral drug-induced liver injury ............................................................................31
Hospital, Port Elizabeth,
South Africa 25. Dyslipidaemia ....................................................................................................................32
6 Anova Health Institute, 26. Immune reconstitution inflammatory syndrome ..............................................................33
Johannesburg ,South Africa
27. Opportunistic infection prophylaxis ..................................................................................34
28. Adherence .........................................................................................................................35
Read online:
Scan this QR 29. Acknowledgments ............................................................................................................36
code with your
smart phone or 30. Abbreviations ....................................................................................................................36
mobile device
to read online.
31. References ........................................................................................................................37

http://www.sajhivmed.org.za 19 Open Access